Is there any connection between the surnames "Copp" and "Cobb&quo

Question:Could it be just a difference in spelling or mis-spelling given many early settlers could not read or write?

Best Answer - Chosen by Asker: Could it be just a difference in spelling or mis-spelling given many early settlers could not read or write?

This is what www.ancestry.com has to say about both names,

Copp
English: topographic name for someone who lived on the top of a hill, from Middle English coppe, Old English copp ‘summit’ (a transferred sense of copp ‘head’, ‘bowl’, cognate with modern English cup), or a habitational name from Copp in Lancashire, named with this word.
English: nickname for someone with a large or deformed head, from Middle English cop(p) ‘head’ (the same word as in 1 above).
Respelling of German Kopp.

Cobb
from the Middle English byname or personal name Cobbe, Cobba, or its Old Norse cognate Kobbi, which are probably from an element meaning ‘lump’, used to denote a large man.
from a reduced form of Jacob.
hope this helps.

I suspect, from the number of times we get to a restaurant and hear "Oh yes, Mr. [Back / Park / Pork / Pat] , your table is ready for you" that some Copps got recorded as Cobbs and vice versa.

That doesn't mean the names are the same, or come from the same place; just that some of our ancestors got recorded wrong some of the time. You (and everyone else who hunts dead ancestors) would be well advised to check for alternate spellings.